Current status of radioactive seed for localization of non palpable breast lesions
Received 10 March 2009; received in revised form 26 May 2009 published online 03 December 2009.
Abstract
Background
Wire-localized breast biopsy (WLBB) remains the standard method for the surgical excision of nonpalpable breast lesions. Because of many of its shortcomings, most important a high microscopic positive margin rate, alternative approaches have been described, including radioactive seed localization (RSL). This review highlights the literature regarding RSL, including safety, the ease of the procedure, billing, and oncologic outcomes.
Methods
Medline and PubMed were searched using the terms “radioactive seed” and “breast.” All peer-reviewed studies were included in this review.
Conclusions
RSL is a promising approach for the resection of nonpalpable breast lesions. It is a reliable and safe alternative to WLBB. RSL is at least equivalent compared with WLBB in terms of the ease of the procedure, removing the target lesion, the volume of breast tissue excised, obtaining negative margins, avoiding a second operative intervention, and allowing for simultaneous axillary staging.
ABSTRACT